ESSAY ALERT!!
I would utilise cyberbrain and prosthetics technology if it was available and of a relatively low risk, and held distinctive advantages. I, for example, find reading the printed word a hardship. In the future (this is looking a long way on, but it's something that GiTS has touched on) cyberbrains could allow for vastly improved text and visual recognition, allowing you to absorb a novel in only a few hours or even minutes, and even read in greatly more dense blocks of data in 2D barcode that could be locked with an encryption key. For the sake of example, a Manga might take up 4 sheets of A4 size paper but contain the pictures and words from an entire volume. Potentially you could even 'read' a movie, then play it back in your brain.
I also have a minor motor skills dysfunction that means I can't write words down correctly, even when I type them on a computer. Letters are often skipped or in the wrong order, even if I consciously look at what I am typing, or writing. I have typed words out like a dummy one letter at a time before now and still missed out a letter without realising. Such problems are usually attributed to problems with co-ordination between the limbs and the brain. This would be another quite common human frailty that could be eliminated by suring up synaptic pathways from the brain to the muscles, ensuring that such 'glitches' did not occur.
More severely disabled people could obviously benefit, being given the ability to use prosthetics to replace lost or non-funtional limbs, have sensory augmentations, or if the technology of GiTS truly comes to pass, side-step terminal illness or crippling disorder or injury by having their ghost loaded to a completely artificial body.
Of course all of the above points raise valid ethical and moral issues. Is it not our individual nuances, including our dysfunction, that make us who we are? To some this is an obvious disadvantage, to others it is the opposite. I believe this will as GiTS intimates create great divides in mankind's society, with factions believing that computers are for the desktop not the human body. I fall on the side of cyberisation myself. I have always seen advantage and intrigue in modern computer technology, but am frustrated by rudimentary human interfaces that do not allow a true human connection to the technology at hand, and with computers becoming so rapidly advancing in both power and function around us the need for more efficient and effective interaction becomes more pressing.
All in all I do believe Shirow's vision of the world of the near future where this level of technology exists is relatively accurate. The time scale is shall we say a little optimistic, but even so people laughed at the thought of every computer being connected to a global network 25 years ago, and when the first personal mirco-computers were produced in the mid-to-late 1970s everyone brushed them off as geek toys that wouldn't catch on...
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